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Attention
No contraceptive method is 100 percent effective. Studies show that fewer than one of each one hundred women correctly using Ortho tricyclen becomes pregnant during the first year of use. Birth contro l methods such as having surgery to become sterile or not having sex are more effective. Using condoms, diaphragms, progestin-only Ortho tricyclen, or spermicides is not as effective as using Ortho tr icyclen containing estrogens and progestins. Discuss with your health care professional your options for birth control.

What special precautions should I follow?
Cigarette smoking increases the risk of serious side effects from Ortho tricyclen, including heart attacks, blood clots, and strokes. This risk is higher for women over 35 years old and heavy smokers (15 or more cigarettes per day). If you take Ortho tricyclen, you should not smoke.

How should you take this medication?
Ortho tricyclen come in packets of 21 or 28 tablets to take by mouth once a day. To avoid upset stomach, take Ortho tricyclen with food or milk. Take the tablet routinely at the same time every day (e .g., after dinner or at bedtime) to help you remember to take the tablet regularly. Missing doses increases your risk of becoming pregnant.

When first starting on this medicine, use an additi onal method of birth control until you have correctly taken 7 days' worth of medicine.

What side effects can this medication cause?
Healthy women who do not smoke cigarettes have almost no chance of having a severe side effect from taking Ortho tricyclen. For most women, more problems occur because of pregnancy than will occur fro m taking Ortho tricyclen. But for some women who have special health problems, Ortho tricyclen can cause some unwanted effects. Some of these unwanted effects include benign (not cancerous) liver tumo rs, liver cancer, or blood clots or related problems, such as a stroke. Although these effects are very rare, they can be serious enough to cause death. You may want to discuss these effects with your doctor.

If you suspect that you may have become pregnant, stop taking this medicine immediately and check with your doctor.

How should you take this medication?
Take this medicine with food to help prevent nausea that might occur during the first few weeks. Nausea usually disappears with continued use or if the medicine is taken at bedtime.

When you begin to use Ortho tricyclen, your body will require at least 7 days to adjust before a pregnancy will be prevented. You will need to use an additional birth control method for at least 7 days. Some d octors recommend using an additional method of birth control for the first cycle (or 3 weeks) to ensure full protection. Follow the advice of your doctor or other health care professional.

Tr y to take the doses no more than 24 hours apart to reduce the possibility of side effects and to prevent pregnancy.

Precautions Before Using This Medicine
Liver disease (or history of, including jaundice during pregnancy or oral contraceptive use) or
- Mental depression (or history of)¡XOrtho tricyclen may make these conditions worse or, rarely, ca se them to occur again. Ortho tricyclen may still be a good choice but you may need to be tested more often
- Diabetes mellitus (sugar diabetes)¡XUse of Ortho tricyclen may cause an increase, usu lly only a small increase, in your blood sugar and usually does not affect the amount of diabetes medicine that you take.
- Epilepsy (seizures) (or history of) or
- Heart or circulation prob lems or
- High blood pressure (hypertension) or


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